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Gene Expression Defines Natural Changes in Mammalian Lifespan

(Submitter supplied) Mammals differ more than hundred fold in maximum lifespan, which can be altered in either direction during evolution, but the molecular basis for natural changes in longevity is not understood. Divergent evolution of mammals also led to extensive changes in gene expression within and between lineages. To understand the relationship between lifespan and variation in gene expression, we carried out RNA-seq-based gene expression analyses of liver, kidney and brain of 33 diverse species of mammals. more...
Organism:
Erinaceus europaeus; Suncus murinus; Canis lupus familiaris; Peromyscus leucopus; Acomys cahirinus; Cavia porcellus; Tamias sibiricus; Tadarida brasiliensis; Ursus americanus; Meles meles; Equus caballus; Mesocricetus auratus; Meriones unguiculatus; Sus scrofa; Mus musculus; Petaurus breviceps; Murina leucogaster; Chlorocebus aethiops; Felis catus; Bos taurus; Capra hircus; Oryctolagus cuniculus; Rattus norvegicus
Type:
Expression profiling by high throughput sequencing
23 related Platforms
141 Samples
Download data: GTF, TXT
Series
Accession:
GSE43013
ID:
200043013

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